CARDIOVASCULAR JOURNAL OF AFRICA: VOLUME 14, ISSUE 3, MAY 2003
  1. Title: Ambulatory blood pressure measurement is now indispensable to the good clinical management of hypertension : editorial
    Authors: O'Brien, Eoin
    From: Cardiovascular Journal of South Africa, Vol 14, Issue 3, May / Jun
    Published: 2003
    Pages: p.113-119
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  2. Title: The effect of different apo(a) isoforms on plasminogen activation in black South African subjects : cardiovascular topics
    Authors: Choma, S.R.; Alberts, M.; Potgieter, H.C.; Ojwang, P.J.
    From: Cardiovascular Journal of South Africa, Vol 14, Issue 3, May / Jun
    Published: 2003
    Pages: p.120-124
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    Abstract: Objective : The present study evaluates the effect of different apolipoprotein(a) [apo(a)] isoforms on plasminogen activation.
    Design : A cross-sectional study.
    Setting : A rural village (Dikgale district ) in the Northern Province of South Africa.
    Subjects : A total of 90 apparently healthy subjects (64 females and 36 males) aged 43 to 67 years participated in the study.
    Results : The mean lipoprotein(a) [Lp(a)] level in the subjects was 38.14 ± 22.34 mg / dl. No association was found between Lp(a) levels and apo(a) isoforms. When the ratio of Lp(a) : plasminogen was less than 1.3, a competitive inhibition was observed, but when the ratio exceeded 1.3, an uncompetitive inhibition was observed with all isoforms.
    Conclusion : The results of the present study suggest that the inhibition of plasminogen activation by Lp(a) is not dependent on apo(a) size.
     
  3. Title: Risk factors and methylenetetrahydrofolate reductase gene polymorphisms in a young South African Indian-based population with acute myocardial infarction : cardiovascular topics
    Authors: Ranjith, N.; Pegoraro, R.J.; Rom, L.
    From: Cardiovascular Journal of South Africa, Vol 14, Issue 3, May / Jun
    Published: 2003
    Pages: p.127-132
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    Abstract: Although coronary heart disease (CHD) is extremely common in South African Indians, there is little published data on the possible causes leading to myocardial infarction (MI) in young Indians. The aim of this study was to identify common environmental risk factors and to examine the relationship between two polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene, the 677 C→T and 1298 A→C in young South African Indians with MI.
    Demographic and risk factor data were obtained from 245 patients ≤ 45 years with MI who were admitted to the RK Khan Hospital, Durban. Venous blood from 195 of the 245 patients with MI, as well as from the siblings of the MI patients (n = 107), and 300 healthy agematched Indian control subjects, were collected for genetic analysis.
    Cigarette smoking was the most important risk factor, occurring in three-quarters of patients, followed by dyslipidaemia in half of the subjects. Diabetes (19%) and hypertension (22%) were found not to be major risk factors for MI. A strong familial link was observed not only for a history of CHD (54%), but also for diabetes (42%) and hypertension (41%).
    No difference was found in the thermolabile variant of the MTFHR gene (677 C→T) or the second variant 1298 A→C between healthy controls and patients with MI or their siblings. The two polymorphisms did not appear to work in synergy, neither was there any relationship to common risk factors for CHD.
    In conclusion, smoking, dyslipidaemia and obesity were the most common phenotypic risk factors for MI. Neither the 677 C→T nor the 1298 A→C MTFHR variants appeared to be risk factors for premature CHD in this group.
     
  4. Title: Evaluation of left ventricular enlargement in the lateral position of the chest using the Hoffman and Rigler sign : cardiovascular topics
    Authors: Freeman, V.; Mutatiri, C.; Pretorius, M.; Doubell, A.
    From: Cardiovascular Journal of South Africa, Vol 14, Issue 3, May / Jun
    Published: 2003
    Pages: p.134-137
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    Abstract: Objective : To evaluate left ventricular enlargement in the lateral projection of the chest using the Hoffman and Rigler sign.
    Background : The Hoffman and Rigler sign for determining left ventricular enlargement was suggested as early as 1965 before the routine use of echocardiography.
    Methods : We studied 136 patients who had had cardiac ultrasound and chest X-rays with lateral projections. We assessed left ventricular size on the lateral projection using the Hoffman and Rigler method (measurement A) and compared this measurement to the value obtained by cardiac ultrasound. The effect of right ventricular size on this measurement was also evaluated.
    Results : The average value of measurement A in all patients with echocardiographic evidence of left ventricular enlargement (LVED above 59 mm) was 19 mm (SD ± 4.03) (95% CI 17.96 to 20.04). Of the 48 patients with a normal size left ventricle on echocardiography, 25.58% had measurement A 18 mm and above, and 13.95% had a value 19 mm and above. Of the 19 patients with right ventricular enlargement (normal left ventricle) on echocardiography, 36.84% had measurement A 18 mm and above, whereas 21.05% had this value 19 mm and above. Measurement A in patients with left ventricular enlargement compared with those with right ventricular enlargement showed a significant difference (p < 0.05).
    Conclusions : When the crossing of the inferior vena cava and the left ventricle can be adequately visualised, the Hoffman and Rigler sign of evaluating left ventricular enlargement in the lateral projection of the chest is a valuable alternative where cardiac ultrasound is not readily available.
     
  5. Title: Multiple cardiac abnormalities in a case of non-mosaic trisomy 8 : case report
    Authors: Hendson, W.; Levin, S.E.; Govendrageloo, K.; Hunter, V.
    From: Cardiovascular Journal of South Africa, Vol 14, Issue 3, May / Jun
    Published: 2003
    Pages: p.138-140
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    Abstract: We present a case of complete trisomy 8 in a 40-day-old male infant, who had a number of congenital heart abnormalities.
     
  6. Title: Enhanced myocardial contractility associated with hypercalcaemia of hyperparathyroidism - a case study in six patients : case report
    Authors: Otto, Anton C.; Nel, Maria G.; Van Staden, Johan A.; Dunn, Marianna; Van Aswegen, Andries; Nel, Riette
    From: Cardiovascular Journal of South Africa, Vol 14, Issue 3, May / Jun
    Published: 2003
    Pages: p.141-143
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    Abstract: The possible association of increased left ventricular ejection fraction (LVEF) in patients with increased serum Ca2+ was observed in our clinic. Six patients with confirmed primary hyperparathyroidism and hypercalcaemia were studied prospectively. Tc-99m sestamibi gated SPECT was done pre- and postoperatively. The LVEF was abnormally high in all the patients preoperatively, i.e. above the normal reference range (47-61%) as used in our clinic. It decreased in all of them postoperatively, yet in only three patients to values within the normal range. This was associated with normalisation of the serum Ca2+ values. The median of the pre-operative LVEF was 74% and postoperative it was 61.5%. The median difference was 9% with a 95% CI for the median difference for paired data (6; 26). This was statistically significant. Increased LVEF was not previously described as part of the clinical picture of primary hyperparathyroidism. The in vivo effect of chronic hypercalcaemia on LV pump function may need to be revisited.
     
  7. Title: Molecular genetics of cardiomyopathy : changing times, shifting paradigms : review article
    Authors: Moolman-Smook, Johanna C.; Mayosi, Bongani M.; Brink, Paul A.; Corfield, Valerie A.
    From: Cardiovascular Journal of South Africa, Vol 14, Issue 3, May / Jun
    Published: 2003
    Pages: p.145-155
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    Abstract: Congestive heart failure is a major problem in developed and developing countries alike. Primary dysfunction of the heart muscle accounts for a significant proportion of patients with a non-ischaemic cause of heart failure. Application of genetic techniques has facilitated identification of some molecular causes of the inherited form of these diseases, dramatically increasing our understanding of the pathogenesis of these primary, previously termed 'idiopathic', cardiomyopathies over the last few decades. Knowledge of the different causes is beginning to coalesce into aetiological principles underlying the clinically distinguished cardiomyopathies. Hypertrophic cardiomyopathy (HCM) now appears to be a disease caused by a dysfunctional sarcomere, dilated cardiomyopathy (DCM), a disease of myocytic structural instability, and arrhythmogenic right ventricular cardiomyopathy, a disease of accelerated myocyte death. The aetiology of both HCM and DCM probably also involves cardiac energy imbalances, while additional factors modify the clinical expression in all cardiomyopathies. Even though our knowledge of the genetic aetiology of the cardiomyopathies is still incomplete, it already has relevant clinical significance. Elucidation of the full genetic contribution to the development and progression of the cardiomyopathies represents a new challenge in the study of these diseases, and will undoubtedly lead to new therapeutic approaches in the not-too-distant future.
     
  8. Title: Do ACE inhibitors have a real role in coronary artery disease? : drug trends in cardiology
    From: Cardiovascular Journal of South Africa, Vol 14, Issue 3, May / Jun
    Published: 2003
    Pages: p.156
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  9. Title: Dramatic new trial results settle controversy in chronic heart failure : drug trends in cardiology
    From: Cardiovascular Journal of South Africa, Vol 14, Issue 3, May / Jun
    Published: 2003
    Pages: p.157
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  10. Title: Rosuvastatin achieves new standards in lipid management : drug trends in cardiology
    From: Cardiovascular Journal of South Africa, Vol 14, Issue 3, May / Jun
    Published: 2003
    Pages: p.157-158
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  11. Title: Clopidogrel reduces death, stroke, heart attack now and later : drug trends in cardiology
    From: Cardiovascular Journal of South Africa, Vol 14, Issue 3, May / Jun
    Published: 2003
    Pages: p.158-159
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  12. Title: Cholesterol-lowering action of policosanol compares well to that of pravastatin and lovastatin : drug trends in cardiology
    From: Cardiovascular Journal of South Africa, Vol 14, Issue 3, May / Jun
    Published: 2003
    Pages: p.161
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  13. Title: Recent review highlights implications for prevention of cardiovascular disease : drug trends in cardiology
    From: Cardiovascular Journal of South Africa, Vol 14, Issue 3, May / Jun
    Published: 2003
    Pages: p.161-162
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  14. Title: Outcomes data for Atacand(R) : results of the SCOPE study : drug trends in cardiology
    From: Cardiovascular Journal of South Africa, Vol 14, Issue 3, May / Jun
    Published: 2003
    Pages: p.162
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  15. Title: The William Nelson ECG quiz
    From: Cardiovascular Journal of South Africa, Vol 14, Issue 3, May / Jun
    Published: 2003
    Pages: p.164, 168
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  16. Title: Cardio news
    From: Cardiovascular Journal of South Africa, Vol 14, Issue 3, May / Jun
    Published: 2003
    Pages: p.165-166
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The role of C-reactive protein:albumin ratio and neutrophil:lymphocyte ratio in predicting coronary artery disease

Published: 26 March 2024
 
Evaluation of cardiac function in paediatric Wilson’s disease patients with advanced echocardiographic modalities (strain and strain rate echocardiography)

Published: 26 March 2024
 
Comprehensive ABC (HbA1c, blood pressure, LDL-C) control and cardiovascular disease risk in patients with type 2 diabetes mellitus and major depressive disorder in a South African managed healthcare organisation

Published: 25 March 2024
 
The predictive value of triglyceride–glucose index for assessing the severity and MACE of premature coronary artery disease

Published: 21 February 2024
 
Obesity is associated with long-term outcome of catheter ablation of atrial fibrillation in patients with dilated cardiomyopathy

Published: 20 February 2024
 
Successful surgical treatment of left ventricular free wall rupture

Published: 19 February 2024
 
Correlation of osteopontin hormone with TIMI score and cardiac markers in patients with acute coronary syndrome presenting with chest pain

Published: 16 February 2024
 
Delayed diagnosis of cardiac amyloidosis in a West African octogenarian

Published: 12 February 2024
 
Impact of COVID-19 on cardiac surgery outcomes

Published: 12 February 2024
 
Percutaneous coronary intervention facilities in Nigeria

Published: 12 February 2024
 
Association of ratios of monocyte/high-density lipoprotein cholesterol and neutrophil/high-density lipoprotein cholesterol with atherosclerotic plaque type on coronary computed tomography

Published: 26 January 2024
 
Assessment of Tp–Te interval in patients with cardiac AL amyloidosis

Published: 15 January 2024
 
Association between Pfizer-BioNTech mRNA vaccine and myocardial infarction: clinical and angiographic insights

Published: 13 December 2023
 
Investigation of the effects of ellagic, vanillic and rosmarinic acid on reperfusion-induced renal injury

Published: 29 November 2023
 
A novel method that can be used in both the diagnosis and treatment of peripheral arterial disease in diabetics: vibration-mediated dilation

Published: 29 November 2023
 
Predictive values of stress hyperglycaemia and glycosylated haemoglobin on admission for long-term recovery of cardiac function in patients with acute myocardial infarction after primary percutaneous coronary intervention

Published: 22 November 2023
 
The relationship between epicardial adipose tissue and choroidal vascularity index in patients with hypertension

Published: 20 November 2023
 
Improving cardiac function of angiotensin receptor/neprilysin inhibitor in patients with acute myocardial infarction: a systematic review and meta-analysis

Published: 17 November 2023
 
Ultrasonographic assessment and clinical outcomes after deployment of a suture-mediated femoral vascular closure device

Published: 16 November 2023
 
Correlation between carotid intima–media thickness and patient outcomes in coronary artery disease in central South Africa

Published: 16 November 2023
 
Contemporary risk factors associated with ischaemic heart disease in central South Africa: a single-centre study

Published: 06 November 2023
 
Comparison of early postoperative results in patients with and without diabetes with low ejection fraction and normal serum creatinine values who underwent coronary artery bypass operation

Published: 27 October 2023
 
Coronary artery bypass grafting in a patient with situs inversus totalis

Published: 20 October 2023
 
Correlation between maternally expressed gene 3 expression and heart rate variability in heart failure patients with ventricular arrhythmia

Published: 06 October 2023
 
A novel U-shaped relationship between serum klotho and abdominal aortic calcification in the general population

Published: 05 October 2023
 
Echocardiographic multiparameter assessment for patients with heart failure with preserved ejection fraction and atrial fibrillation

Published: 04 October 2023
 
Relationship between adiponectin and copeptin levels with long-term cardiovascular mortality in ST-segment elevation myocardial infarction after percutaneous coronary intervention

Published: 04 October 2023
 
Six months of resistance training improves heart rate variability in the elderly

Published: 27 September 2023
 
Association between serum α-klotho level and the prevalence of heart failure in the general population

Published: 27 September 2023
 
The assessment of thoracal approaches in the treatment of aortic coarctation

Published: 15 September 2023
 
Point-of-care testing compared to gold-standard laboratory methods in the measurement of serum lipids

Published: 31 August 2023
 
Outcomes of single-ventricle physiology in central South Africa

Published: 25 August 2023
 
Comparison of serum lipoprotein(a) levels in young and middle-aged patients presenting for the first time with ST-elevation myocardial infarction: a single-centre study

Published: 25 August 2023
 
The value of measured partial oxygen pressure during pulmonary vein closure and the relationship with the diameter of the closed vein in patients with cryoablation

Published: 17 August 2023
 
Paying more attention to arterial hypertension, dyslipidaemia, women and the rural environment in our ongoing fight against cardiovascular diseases and their risk factors

Published: 17 August 2023
 
The relationship between serum osteoprotegerin levels and right atrial and ventricular speckle-tracking measurements in essential hypertension patients with normal left ventricular systolic function

Published: 27 July 2023
 
The association between CHA2DS2-VASc score and aortic valve sclerosis

Published: 26 July 2023
 
Oxidative metabolism of neutrophils in acute coronary syndrome

Published: 25 July 2023
 
Yield of family screening in dilated cardiomyopathy within low-income setting: Tanzanian experience

Published: 25 July 2023
 
Study of the mechanism of Shexiang Baoxin pill-mediated angiogenesis in acute myocardial infarction

Published: 04 July 2023
 
Effects of intravenous sodium thiosulfate on vascular calcification in dialysis patients with end-stage renal disease: a systematic review and meta-analysis

Published: 03 July 2023
 
Right ventricular function in treatment-naïve human immunodeficiency virus-infected patients

Published: 03 July 2023
 
Changes in blood pressure after catheter-based renal denervation in South Africa

Published: 28 June 2023
 
Effect of insulin resistance on left ventricular remodelling in essential hypertensives: a cross-sectional study

Published: 21 June 2023
 
Impact of the COVID-19 pandemic on cardiology fellowship training in a sub-Saharan African training centre: an African perspective

Published: 19 June 2023
 
The effects on clinical outcomes of administering medications together or separately in prolonged dual antiplatelet therapy after peripheral revascularisation

Published: 19 June 2023
 
Empagliflozin significantly prevents QTc prolongation due to amitriptyline intoxication

Published: 07 June 2023
 
Is the transradial approach associated with decreased acute kidney injury following percutaneous coronary intervention in patients not complicated by major bleeding and haemodynamic disturbance?

Published: 05 June 2023
 
Effect of lactate levels on extubation time in coronary artery bypass grafting surgery

Published: 05 June 2023
 
Evaluation of clinical results of esmarch bandage application in giant saphenous vein closure during endovenous glue ablation

Published: 03 June 2023
 
Right atrial strain in a normal adult African population according to age

Published: 02 June 2023
 
Long-term experience of the modified David V re-implantation technique for valve-sparing aortic root replacement

Published: 01 June 2023
 
Pre-eclampsia: does cardiac function differ in HIV-positive and -negative women?

Published: 11 May 2023
 
Systemic immune–inflammation index, and neutrophilto-lymphocyte and platelet-to-lymphocyte ratios can predict clinical outcomes in patients with acute coronary syndrome

Published: 05 May 2023
 
A strategy to improve adherence to guidelinedirected medical therapy (GDMT) and the role of the multidisciplinary team in a heart-failure programme

Published: 05 May 2023
 
Association between apelin-12 and creatine kinase-MB, depending on success of reperfusion in STEMI patients

Published: 05 May 2023
 
Investigation of left ventricular changes according to valve type in patients with surgical replacement due to isolated aortic stenosis

Published: 05 May 2023
 
Assessment value of the modified early warning score for long-term prognosis of older patients with chronic heart failure

Published: 28 April 2023
 
A cross-sectional study of the spectrum, aetiology and clinical characteristics of adult mitral valve disease at Chris Hani Baragwanath Academic Hospital

Published: 26 April 2023
 
Identification and treatment of asymptomatic central venous catheter thrombosis after TAVI

Published: 24 April 2023
 
Surgical experience in adults with Ebstein’s anomaly: long-term results

Published: 24 March 2023
 
Effect of different priming fluids on extravascular lung water, cell integrity and oxidative stress in cardiopulmonary bypass surgery

Published: 06 March 2023
 
Calcified right ventricular fibroma in an adult

Published: 03 March 2023
 
Arterial stiffness assessment in obese black South African patients

Published: 13 February 2023
 
Clinical characteristics, diagnostic methods and results of surgically treated histologically benign cardiac myxomas

Published:07 February 2023
 
Characteristics and immediate outcomes of patients who underwent percutaneous balloon mitral valvuloplasty at the Jakaya Kikwete Cardiac Institute, Tanzania

Published:06 February 2023
 
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