| FROM THE EDITORS DESK | 6 |
| CARDIOVASCULAR TOPICS | 7 |
| Management of acute coronary syndrome in South Africa: insights from the ACCESS (Acute Coronary Events – a Multinational Survey of Current Management Strategies) registry | 7 |
| Social drift of cardiovascular disease risk factors in Africans from the North West Province of South Africa: the PURE study | 13 |
| Target-organ damage and cardiovascular complications in hypertensive Nigerian Yoruba adults: a cross-sectional study | 31 |
| William Nelson | 36 |
| Prevalence of cardiac dyssynchrony and correlation with atrio-ventricular block and QRS width in dilated cardiomyopathy: an echocardiographic study | 37 |
| Different lipid profiles according to ethnicity in the Heart of Soweto study cohort of de novo presentations of heart disease | 41 |
| Effect of perindopril on pulse-wave velocity and endothelin-1 in black hypertensive patients | 48 |
| The effect of the metabolic syndrome on the risk and outcome of coronary artery bypass graft surgery | 52 |
| REVIEW ARTICLE | 57 |
| SA HEART CONFERENCE REPORTS | 64 |
| CASE REPORTS | 69 |
| Severe cardiac failure due to rapidly progressive rheumatoid arthritis-associated valvulopathy | 69 |
| HIV infection, pulmonary arterial hypertension and pregnancy: a fatal triad | 72 |
| Triple papillary fibroelastomas in an asymptomatic patient | 75 |
| Cardiac mass in a patient with sigmoid adenocarcinoma: a metastasis? | 78 |
| Isolated lower limb ischaemia as an unusual presenting symptom of aortic dissection | 81 |