| Tribute: Professor Andries Jacob Brink | 6 |
| EDITORIAL | 6 |
| CARDIOVASCULAR TOPICS | 8 |
| Right ventricular dysfunction in a hypertensive population stratified by patterns of left ventricular geometry | 8 |
| Doppler echocardiographic indices in aortic coarctation: a comparison of profiles before and after stenting | 13 |
| A comparative study of amoxicillin, clindamycin and chlorhexidine in the prevention of post-extraction bacteraemia | 21 |
| Comparison of outcomes in ST-segment depression and ST-segment elevation myocardial infarction patients treated with emergency PCI: data from a multicentre registry | 25 |
| Elevated salivary C-reactive protein predicted by low cardio-respiratory fitness and being overweight in African children | 31 |
| William Nelson ECG Quiz | 20 |
| REVIEW ARTICLE | 37 |
| DRUG TRENDS | 52 |
| European Society of Cardiology congress 2012, Munich, Germany. New ESC guidelines on atrial fibrillation accept reality of next generation of anti-coagulants | 52 |
| Renal denervation in Symplicity trials and real-life setting continue to show significant blood pressure reduction in all treatment groups | 54 |
| Rivaroxaban in acute coronary syndromes and atrial fibrillation: rivaroxaban shown to reduce cardiovascular deaths in STEMI patients | 55 |
| Ivabradine reduces total hospital burden in heart failure | 58 |
| GARFIELD: a window on the real-life treatment of atrial fibrillation. South Africa joins the GARFIELD registry | 58 |
| CASE REPORTS - PUBLISHED ONLINE | 59 |
| Acute anterior myocardial infarction in an 85-year-old male patient, complicated by the deadly duo: ventricular septal rupture and pseudoaneurysm | 59 |
| Giant pseudoaneurysm of the left axillary artery following a stab wound | 62 |
| Acute ST-elevation inferior myocardial infarction in a patient with a non-obstructive mechanical mitral valve thrombosis | 65 |
| Prolonged coagulopathy related to coumarin rodenticide in a young patient: superwarfarin poisoning | 67 |