The Cardiovascular Journal of Africa (CVJA) is an international peer-reviewed journal that keeps cardiologists up to date with advances in the diagnosis and treatment of cardiovascular disease.

Topics covered include coronary disease, electrophysiology, valve disease, imaging techniques, congenital heart disease (fetal, paediatric & adult), heart failure, surgery & basic science. CVJA is the official journal of the PASCAR and has been published since 1990.

Important Notice to all Authors: Manuscript Processing Fee (effective 1 January 2016)

It has become necessary for the Cardiovascular Journal of Africa to charge a modest manuscripts processing fees for all articles submitted for publication.
  • South African and African Authors: ZAR 1000
  • International Authors: ZAR 2000
This is normal for most, if not all, journals. We so far have been able to survive without charging authors for submissions but can no longer do so. We regret that we have to implement this as from the 1st of January 2016. Payment will need to be made online and once payment has been received, the manuscript will be further processed for possible publication.

This payment is a processing fee and does not guarantee publication of the article. The processing fee is not refundable in the event of rejection as processing cost will have been incurred. (Payment can be made online with a valid credit card)
Cardiovascular Journal of Africa: Volume 27, Issue 2, March / April 2016

• Cardiovascular pathology
• Pre-eclampsia
• Pre-conception counselling
• Medical disease and maternal mortality
• Physiological changes in pregnancy
• Diagnosing cardiac disease
• Hypertensive disorders
• Valvular heart disease
• Perinatal depression

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cardiovascular disease
Cardiovascular Journal of Africa: Volume 27, Issue 1, January / February 2016

• Filamin C: a novel component of the KCNE2 interactome during hypoxia
• Anatomical factors affect mortality rates after endovascular aneurysm repair
• ECG abnormalities and dyslipidaemic syndrome in sickle cell anaemia
• FTO rs9939609 and MC4R rs17782313: elevated nocturnal blood pressure
• Left ventricular systolic function in Nigerian children infected with HIV/AIDS
• Vascular rings: a radiological review of anatomical variations
• Change in right ventricular systolic function according to revascularisation method

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cardiovascular disease
Cardiovascular Journal of Africa: Volume 26, Issue 6, November / December 2015

• Heart-type fatty acid-binding protein as diagnostic marker of non-STEMI
• Topical beta-blocker-induced atrioventricular block
• Interatrial conduction delay with polycystic ovary syndrome
• Protective effects of ginseng extracts on ischaemia–reperfusion injury
• An open-access mobile, electronic patient register for RHD
• Peri-operative myocardial injury and apoptosis during CABG surgery

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cardiovascular disease
Cardiovascular Journal of Africa: Volume 26, Issue 5, PASCAR Congress Abstracts

Joint congress between the Pan-African Society of Cardiology and the Cardiovascular Society of Mauritius. Intercontinental Resort, Balaclava Fort, Mauritius, 3 - 7 October 2015.

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cardiovascular disease
Cardiovascular Journal of Africa: Volume 26, Issue 4, July / August 2015

• Hypertension in sub-Saharan Africa
• Analysis of clinical outcomes of IABP
• Efficacy of milk and lemon juice during MPI
• Risk factors for CKD in Uganda
• Performance of re-used pacemakers and ICDs
• Glycaemic, BP and cholesterol control in diabetics
• First Melody® valve implantations in Africa

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cardiovascular disease
Cardiovascular Journal of Africa: Volume 26, Issue 3, May / June 2015

 • RV function and hepatosteatosis in non-alcoholic fatty liver disease
• Left atrial function and conduction in Maras powder users and smokers
• Postoperative atrial fibrillation with left atrial myxoma
• Sickle cell trait and chronic kidney disease in Congolese patients
• Clinical outcomes of IABP during coronary artery bypass surgery
• Anaemia among heart failure patients at Brazzaville Hospital
• Antibiotic recipe for arrhythmic disaster
• Unusual cause of large fibrinous pericardial effusion
• Heparin-induced thrombocytopenia with thrombosis

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cardiovascular disease
Cardiovascular Journal of Africa: Volume 26, Issue 2,  March / April 2015

H pylori infection in HIV-infected Africans on HAART
• Dietary salt intake among medical students in Angola
TNNI3 gene mutations in South African patients
• HIV-associated large-vessel vasculopathy
• PASCAR Hypertension Task Force meeting
• Spontaneous coronary artery dissection
• Sudden cardiac death in low-resource settings
• Cardiac sarcoidosis in pregnant women with arrhythmia
• Radiofrequency ablation on a morbidly obese patient
• May–Thurner syndrome with inconsistent findings

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National Advisory Committee for the Prevention and Control of Rheumatic Fever and Rheumatic Heart Disease in Namibia

In Windhoek, Namibia, Thursday 23 April 2015 marked a historic milestone for the Pan-African campaign to arrest the march of rheumatic fever (RF) and rheumatic heart disease (RHD) throughout our continent. Under the authority of the Minister of Health and Social Services, Dr Bernard Haufiku, the first meeting of the National Advisory Committee on Rheumatic Fever and Rheumatic Heart Disease began to elaborate on a plan for the prevention and control of a heart disease, which, it is estimated, claims the lives of 1.4 million people in less well-resourced countries globally every year. The prevalence in Africa is as high as 30/1 000 among school children.

Among survivors, RHD is a major cause of morbidity through heart failure, atrial fibrillation and cerebrovascular accidents. RHD results in school absenteeism in about two-thirds of affected learners, and because the disease progresses during early adulthood and causes chronic disability, it has the potential to undermine national productivity. The economic impact of RHD in the African region is profound and was estimated at US$791 million to 2.37 billion in 2010.

Significantly, Namibia is the first African country to tackle the prevention and control of RHD in this manner at a national level. The national programme was launched in March 2014 by Dr Richard Kamwi, the health minister at that time. Advocacy for the national programme had been informed by research conducted by the Namibian National Registry of RF and RHD, which is an important partner in the Global Registry of RF and RHD.

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cardiovascular disease
South African hospital the first in the Middle East, Africa, central Asia and Turkey to implant the world’s smallest, minimally invasive cardiac pacemaker

Groote Schuur Hospital in Cape Town is the first hospital in the Middle East, Africa, central Asia and Turkey to implant the world’s smallest pacemaker: the Medtronic Micra™ transcatheter pacing system (TPS). The device was implanted recently as part of the Medtronic global pivotal clinical trial.

One-tenth the size of a conventional pacemaker and comparable in size to a large vitamin, the Micra TPS pacemaker is delivered directly into the heart through a catheter inserted into the femoral vein. Once positioned, the pacemaker is securely attached to the heart wall and can be repositioned if needed. The miniature device does not require the use of wires, known as ‘leads’, to connect to the heart. Attached to the heart via small tines, the pacemaker delivers electrical impulses that pace the heart through an electrode at the end of the device.

‘This miniaturised technology is designed to provide patients with the advanced pacing technology
of traditional pacemakers via a minimally invasive approach’, said Dr Ashley Chin, consultant cardiologist/electrophysiologist at Groote Schuur Hospital and the University of Cape Town, who implanted this first Micra TPS. ‘We are proud that Groote Schuur Hospital was selected among an elite group of institutions to take part in this global clinical trial. If positive, the results of the trial could potentially benefit the more than one million people globally who receive pacemakers each year.’

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cardiovascular disease
Special Supplement to CVJA Volume 26, Issue 2: H3Africa comes of age

With the advent of technology that made possible large-scale sequencing and genotyping studies, it quickly became apparent that the demographic history of our species had been recorded in the genome and we could reconstruct our wanderings across the globe by studying DNA. While the vast majority of genetic variation is shared among continental populations, the most prominent finding from these early surveys of regional populations was the substantially greater degree of heterozygosity found in contemporary African populations. The ‘out of Africa’ story has long been a central dogma in paleoanthropology, and the rich cultural and linguistic heritage of the continent has also been well documented; yet the implications of this phase of human history for biomedicine had never been fully appreciated.

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cardiovascular disease
Social support and management of hypertension in south-west Nigeria

Social support can facilitate compliance or adherence to recommended treatment regimens, especially for chronic disease management. There is little data from Africa on the role of social support in the management of chronic disease.

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The Cardiovascular Journal of Africa has launched an Online First Advance Online Publication (ePublication ahead of print) with full text availability via Pubmed and this website which is accessible via Google and other search engines.

This facility is also known internationally as e-publication, ahead of print and offers authors the opportunity to publish their research articles sooner for an international audience. Read More »
Associations between body fat distribution, insulin resistance and dyslipidaemia in black and white South African women

Published: 25 May 2016
Determinants of change in body weight and body fat distribution over 5.5 years in a sample of free-living black South African women

Published: 25 May 2016
Endothelial dysfunction and arterial stiffness in pre-eclampsia demonstrated by the EndoPAT method

Published: 19 May 2016
Short-term warfarin treatment for apical thrombus in a patient with Takotsubo cardiomyopathy

Published: 19 May 2016
Adropin as a potential marker of enzyme-positive acute coronary syndrome

Published: 19 May 2016
Strain and strain rate echocardiography in children with Wilson’s disease

Published: 13 May 2016
Non-dipper hypertension is associated with slow coronary flow among hypertensives with normal coronary angiogram

Published: 13 May 2016
A comparison of off- and on-pump beating-heart coronary artery bypass surgery on long-term cardiovascular events

Published: 11 May 2016
Epidemiology and patterns of hypertension in semi-urban communities, south-western Nigeria

Published: 11 May 2016
Effects of a PPAR-gamma receptor agonist and an angiotensin receptor antagonist on aortic contractile responses to alpha receptor agonists in diabetic and/or hypertensive rats

Published: 04 May 2016
Comparison of primary repair and patch plasty procedure on the P wave in adult atrial septal defect closure

Published: 04 May 2016
The relationship between elevated magnesium levels and coronary artery ectasia

Published: 21 April 2016
Successful continuous-flow left ventricular assist device implantation with adjuvant tricuspid valve repair for advanced heart failure

Published: 12 April 2016
Procedural and one-year clinical outcomes of bioresorbable vascular scaffolds for the treatment of chronic total occlusions: a single-centre experience

Published: 12 April 2016
Simultaneous presentation of giant aneurysms of the coronary sinus and superior vena cava

Published: 12 April 2016
Should patients undergo ascending aortic replacement with concomitant cardiac surgery?

Published: 12 April 2016
Patient outcomes following after-hours and weekend admissions for cardiovascular disease in a tertiary hospital in Calabar, Nigeria

Published: 12 April 2016
Could the novel ‘double-hole’ technique be an alternative for the inflow occlusion method?

Published: 12 April 2016
A case of enoxaparin-induced thrombocytopaenia during treatment of acute myocardial infarction

Published: 12 April 2016
Gender-based differences in the relationship between fatty liver disease and atherosclerosis.

Published: 14 March 2016
High aortic pulse-wave velocity may be responsible for elevated red blood cell distribution width in overweight and obese people: a community-based, cross-sectional study.

Published: 19 February 2016
Comparison of two different techniques for balloon sizing in percutaneous mitral balloon valvuloplasty: which is preferable?

Published: 26 January 2016
Clinical features and patency rates of Remedy® biodegradable peripheral stents.

Published: 26 January 2016
Seven key actions to eradicate rheumatic heart disease in Africa: the Addis Ababa communiqué.

Published: 12 January 2016
Administration of perivascular cyanoacrylate for the prevention of cellular damage in saphenous vein grafts: an experimental model.

Published: 28 October 2015
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