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CARDIOVASCULAR JOURNAL OF AFRICA • Vol 24, No 2, March 2013

34

AFRICA

Review Article

Epidemiology of ischaemic heart disease in sub-Saharan

Africa

CHURCHILL LUKWIYA ONEN

Abstract

Background:

The epidemiology of ischaemic heart disease

(IHD) in sub-Saharan Africa (SSA) remains largely enig-

matic. Major obstacles to our understanding of the condition

include lack of reliable health statistics, particularly cause-

specific mortality data, inadequate diagnostic capabilities,

shortage of physicians and cardiologists, and misguided

opinions.

Methods:

This review of the epidemiology of ischaemic heart

disease in sub-Saharan Africa involved a systematic biblio-

graphic MEDLINE search of published data on IHD in SSA

over the past century. Search words included epidemiology,

ischaemic (coronary) heart disease, myocardial infarction,

cardiovascular risk factors and sub-Saharan Africa. Selected

data are presented on the prevalence of cardiovascular risk

factors and mortality from ischaemic heart disease from

different countries representing the main regions of the

continent.

Results:

Although IHD in SSA remains relatively uncommon,

its prevalence is predicted to rise in the next two decades due

to the rising prevalence of risk factors, especially hyperten-

sion, diabetes, overweight and obesity, physical inactivity,

increased tobacco use and dyslipidaemia. It is estimated that

age-standardised mortality rates for IHD will rise by 27%

in African men and 25% in women by 2015, and by 70 and

74%, respectively by 2030.

Conclusion:

Ischaemic heart disease remains relatively

uncommon in SSA, despite an increasing prevalence of risk

factors, but its incidence is rising. The pace and direction of

economic development, rates of urbanisation, and changes in

life expectancy resulting from the impact of pre-transitional

diseases and violence will be major determinants of the IHD

epidemic in SSA. The best window of opportunity for preven-

tion of the emerging epidemic of ischaemic heart disease in

sub-Saharan Africa is now.

Keywords:

epidemiology, ischaemic heart disease, sub-Saharan

Africa

Submitted 23/1/12, accepted 16/10/12

Cardiovasc J Afr

2013;

24

: 34–42

www.cvja.co.za

DOI: 10.5830/CVJA-2012-071

‘a riddle wrapped in a mystery inside an enigma’

1 October, 1939

Sir Winston Churchill, British orator, author and Prime Minister

(1874–1965)

Over a century ago, Sir Winston Churchill, a renowned British

statesman and leader during the Second World War (WWII),

made a celebrated visit to Uganda, where he was so moved as to

describe it as ‘the Pearl of Africa’. Sir Winston, referring to the

quality of intelligence gathered by Western allies during WWII,

called Russia a ‘riddle wrapped in a mystery inside an enigma’.

While the same phrase could be used today to describe the

epidemiology of ischaemic heart disease (IHD) in sub-Saharan

Africa (SSA) because of many puzzles and lingering myths,

what is enigmatic is the contempt with which the potential

threat of IHD has been treated at various levels of health sectors,

governments and international agencies. A recent change in

posture by World Health Organisation (WHO) Regional Office

for Africa, with greater focus on non-communicable disease

(NCD), and the United Nations high-level meeting on NCD

prevention and control in New York on 19–20 September 2011

are good indicators of the recognition of the importance of

NCDs and the rapidly unfolding epidemiological landscape

catalysed by the birth of conjoined twins, infectious diseases and

non-communicable diseases.

The 30th anniversary of the Pan-African Society of Cardiology

(PASCAR) conference along with the Third All-Africa

Conference on Heart Disease, Diabetes and Stroke took place

at Munyonyo Speke Resort in Kampala on the shores of Lake

Victoria in May 2011. The warmth of the land, the gentle tropical

rain showers interspersed with bright sunshine, and above all, the

friendliness of Ugandans must have pervaded the hearts of most

foreign delegates to the conference.

This review article will focus on some of the obstacles to our

understanding of IHD in SSA. A synopsis of cardiovascular risk

factors and their role in IHD in SSA, and selected mortality data

on IHD from various countries across the continent are presented

in this article. A plea for urgent and concerted action to avert the

impending epidemic of IHD in SSA is made.

Obstacles to our understanding of IHD in SSA

Major obstacles to our understanding of IHD in SSA include

lack of reliable statistics on health, life expectancy and disease

incidence, and the absence of cause-specific mortality data.

This is confounded by lack of diagnostic capabilities in most

of SSA, emanating from a shortage of physicians, particularly

cardiologists, and lack of appropriate investigations, such as

Centre for Chronic Diseases, Gaborone, Botswana

CHURCHILL LUKWIYA ONEN, MD FRCP,

onenkede@info.bw