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ISSN 1995-1892 (print)

ISSN 1680-0745 (online)

Cardiovascular Journal of Africa

www.cvja.co.za

CONTENTS

INDEXED AT SCISEARCH (SCI), PUBMED, PUBMED CENTRAL AND SABINET

Vol 30, No 5, SEPTEMBER/OCTOBER 2019

EDITORS

Editor-in-Chief

(South Africa)

PROF PAT COMMERFORD

Assistant Editor

PROF JAMES KER (JUN)

Regional Editor

DR A DZUDIE

Regional Editor (Kenya)

DR F BUKACHI

Regional Editor (South Africa)

PROF R DELPORT

EDITORIAL BOARD

PROF PA BRINK

Experimental & Laboratory

Cardiology

PROF R DELPORT

Chemical Pathology

PROF MR ESSOP

Haemodynamics, Heart Failure

& Valvular Heart Disease

DR OB FAMILONI

Clinical Cardiology

DR V GRIGOROV

Invasive Cardiology & Heart

Failure

PROF J KER (SEN)

Hypertension, Cardiomyopathy,

Cardiovascular Physiology

DR J LAWRENSON

Paediatric Heart Disease

INTERNATIONAL

ADVISORY BOARD

PROF DAVID CELEMAJER

Australia (Clinical Cardiology)

PROF KEITH COPELIN FERDINAND

USA (General Cardiology)

DR SAMUEL KINGUE

Cameroon (General Cardiology)

DR GEORGE A MENSAH

USA (General Cardiology)

PROF WILLIAM NELSON

USA (Electrocardiology)

DR ULRICH VON OPPEL

Wales (Cardiovascular Surgery)

PROF PETER SCHWARTZ

Italy (Dysrhythmias)

PROF ERNST VON SCHWARZ

USA (Interventional Cardiology)

SUBJECT EDITORS

Nuclear Medicine and Imaging

DR MM SATHEKGE

Heart Failure

DR G VISAGIE

Paediatric

DR S BROWN

Paediatric Surgery

DR DARSHAN REDDY

Renal Hypertension

DR BRIAN RAYNER

Surgical

DR F AZIZ

Adult Surgery

DR J ROSSOUW

Epidemiology and Preventionist

DR AP KENGNE

Pregnancy-associated Heart

Disease

PROF K SLIWA-HAHNLE

PROF A LOCHNER

Biochemistry/Laboratory

Science

DR MT MPE

Cardiomyopathy

PROF DP NAIDOO

Echocardiography

PROF B RAYNER

Hypertension/Society

PROF MM SATHEKGE

Nuclear Medicine/Society

PROF YK SEEDAT

Diabetes & Hypertension

PROF H DU T THERON

Invasive Cardiology

EDITORIALS

247 Familial hypercholesterolaemia and its management in South Africa

AD Marais

249 Renal denervation: bleak past, brighter future

B Rayner

CARDIOVASCULAR TOPICS

251 The effects of HIV/AIDS on the clinical profile and outcomes post pericardiectomy of

patients with constrictive pericarditis: a retrospective review

DP Naidoo • G Laurence • B Sartorius • S Ponnusamy

258 Ellisras Longitudinal Study 2017: association of hypertension with increasing levels of

adiposity in 10- to 14-year-old boys and girls in the Eastern Cape (ELS 31)

A Chungag • CM Tata • CR Sewani-Rusike • W Nel • BN Nkeh-Chungag

262 Ellisras Longitudinal Study 2017: patterns of physical activity in an urban and rural

setting among black South African adults (ELS 23)

ZS Mabweazara • LL Leach • M Smith • L Tsolekile • T Puoane

268 Effects of atorvastatin on time-dependent change of fast sodium current in simulated

acute ischaemic ventricular myocytes

H Li • Z Wan • X Li • T Teng • X Du • J Nie

275 Effects of cardiopulmonary bypass on dialysis-dependent patients

N Tanrıkulu • B Ozbek

279 Long-term safety and efficacy of alirocumab in South African patients with heterozygous

familial hypercholesterolaemia: the ODYSSEY Open-Label Extension study

DJ Blom • J Breedt • LJ Burgess • IO Ebrahim • G Ellis • P Soma • E van der Walt • P Naidoo

• A van Tonder • FJ Raal